Across TCGA patient cohorts, C5orf66 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,143 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C5orf66-associated proteins across cancer lineages are HNRNPAB, CHAF1A_S65, and AHCTF1_S1142. Each is linked with C5orf66 in more than 4 cancer types. Because this analysis shows association rather than direction, both C5orf66-to-partner and partner-to-C5orf66 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf66→partner) and Y-score (partner→C5orf66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HNRNPAB →	+0.518	+0.289	<.001	<.001	3	5
LSCC	CHAF1A_S65 →	+0.894	+0.860	<.001	<.001	3	4
PDAC	AHCTF1_S1142 →	+0.910	+0.351	<.001	.002	3	4
GBM	DHX9 →	+0.297	+0.284	<.001	<.001	3	4
GBM	DPYSL2 →	-0.338	-0.233	<.001	.009	3	4
CCRCC	AKAP12_S627 →	-0.645	-0.261	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,143 associations by consensus.

Exploration

C5orf66 survival (RNA) · tumor vs normal (RNA) · all C5orf66 data types