C5orf64-AS1

Across TCGA pan-cancer cohorts, C5orf64-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated C5orf64-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher C5orf64-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated C5orf64-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and PAAD show a favorable association.

BRCA, LGG, and UCEC are the cancer types where C5orf64-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	All	0.858	0.912	<.001	54	view →
LGG	OS	Median	All	0.951	0.842	<.001	44	view →
UCEC	DFS	Tertile	All	0.824	0.910	.006	30	view →
PAAD	DFS	Median	II,III,IV	0.397	0.244	.002	29	view →
LIHC	OS	Median	III,IV	0.334	0.666	.001	27	view →
KIRC	OS	Tertile	All	0.716	0.575	.007	18	view →
ESCA	OS	Tertile	III,IV	0.662	0.338	.006	18	view →
OV	DFS	Quartile	IV	0.293	0.501	.017	18	view →
DLBC	OS	Tertile	II,III,IV	0.586	0.949	.014	18	view →
ACC	OS	Tertile	All	0.214	0.820	.006	18	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	15	view →
PRAD	DFS	Tertile	All	0.894	0.727	.001	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

C5orf64-AS1–BRCA (DFS)

Open the BRCA breakdown →