Across TCGA patient cohorts, C5orf60 mutation is significantly associated with the RNA expression of many other genes, with 86 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C5orf60-associated genes across cancer lineages are RNU6-129P, MIR6799, and SPATA31A5. Each is linked with C5orf60 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf60-to-partner and partner-to-C5orf60 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf60→partner) and Y-score (partner→C5orf60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-129P →	+0.155	+4.414	<.001	.004	3	2
BRCA	MIR6799 →	+0.377	+5.506	.003	.005	3	1
BRCA	SPATA31A5 →	+0.003	+7.471	<.001	.008	3	1
BRCA	MIR6802 →	+0.484	+7.234	<.001	<.001	3	1
UCEC	MTRNR2L2 →	+0.517	+2.452	.007	.004	3	1
UCEC	BMP1 →	-0.685	-3.448	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

Exploration

C5orf60 survival (RNA) · tumor vs normal (RNA) · all C5orf60 data types