C5orf52

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C5orf52 RNA expression is significantly associated with the mutation status of many other genes, with 229 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C5orf52-associated genes across cancer lineages are MTMR3, SPZ1, and GYS2. Each is linked with C5orf52 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf52-to-partner and partner-to-C5orf52 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf52→partner) and Y-score (partner→C5orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEMTMR3 →+3.977+0.016.007<.00132
SOFT_TISSUESPZ1 →+5.977+0.033.001<.00132
LUNG_NSCLC_LUADGYS2 →+3.813+0.065.001<.00132
LUNG_NSCLC_LUADPCDHA10 →+4.228+0.076<.001<.00132
BLOOD_LymphomaSTAB1 →+3.662+0.013.009<.00132
BLOOD_LymphomaCSRNP1 →+6.247+0.036<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 229 associations by consensus.

Exploration