Across TCGA cell cohorts, C5orf51 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C5orf51-associated genes across cancer lineages are TPD52L3, TECRL, and AMELY. Each is linked with C5orf51 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf51-to-partner and partner-to-C5orf51 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf51→partner) and Y-score (partner→C5orf51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TPD52L3 →	+0.051	+3.684	<.001	.006	3	1
LARGE_INTESTINE	TECRL →	+0.017	+4.562	<.001	<.001	3	1
LARGE_INTESTINE	AMELY →	+0.036	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

C5orf51 survival (RNA) · tumor vs normal (RNA) · all C5orf51 data types