C5orf34

Across TCGA patient cohorts, C5orf34 mutation is significantly associated with the RNA expression of many other genes, with 1,546 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C5orf34-associated genes across cancer lineages are SNRPCP20, MIR3159, and RN7SL483P. Each is linked with C5orf34 in more than 2 cancer types. Because this analysis shows association rather than direction, both C5orf34-to-partner and partner-to-C5orf34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPCP20 grouped by C5orf34-low versus C5orf34-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf34→partner) and Y-score (partner→C5orf34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SNRPCP20 →	+0.228	+3.669	<.001	.006	3	3
HNSC	MIR3159 →	+0.607	+5.368	<.001	.005	3	3
UCEC	RN7SL483P →	+0.152	+2.001	<.001	.004	3	3
COAD	BPY2DP →	+0.238	+6.409	<.001	<.001	3	3
HNSC	RNA5SP115 →	+0.465	+5.303	<.001	.006	3	2
SKCM	RNU6-150P →	+0.247	+5.219	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,546 associations by consensus.

SNRPCP20 by C5orf34 expression — SKCM

Explore this box plot interactively →