C5orf34

Across TCGA cell cohorts, C5orf34 mutation is significantly associated with the mutation status of many other genes, with 723 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C5orf34-associated genes across cancer lineages are NID1, NINL, and GPR149. Each is linked with C5orf34 in more than 2 cancer types. Because this analysis shows association rather than direction, both C5orf34-to-partner and partner-to-C5orf34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NID1 grouped by C5orf34-low versus C5orf34-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf34→partner) and Y-score (partner→C5orf34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	NID1 →	+3.357	+4.285	.005	.005	1	3
LUNG_NSCLC_LUAD	NINL →	+4.000	+4.303	.001	.001	1	3
LUNG_NSCLC_LUAD	GPR149 →	+5.584	+4.924	<.001	<.001	1	2
LUNG_NSCLC_LUAD	ASTL →	+5.000	+4.187	.008	.008	1	2
LUNG_NSCLC_LUAD	ANKRD13B →	+5.000	+4.187	.008	.008	1	2
LUNG_NSCLC_LUAD	CASTOR1 →	+5.000	+4.187	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 723 associations by consensus.

NID1 by C5orf34 expression — STOMACH

Explore this box plot interactively →