C5orf24

Across TCGA pan-cancer cohorts, C5orf24 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C5orf24 data layer compared with 26 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher C5orf24 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C5orf24 expression acts as an unfavorable survival marker.

HNSC, LUSC, and LIHC are the cancer types where C5orf24 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.169	0.751	<.001	42	view →
LUSC	OS	Median	All	0.168	0.675	.023	18	view →
LIHC	OS	Median	All	0.059	0.783	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

C5orf24–HNSC (OS)

Open the HNSC breakdown →