C5orf24

Across TCGA patient cohorts, C5orf24 protein abundance is significantly associated with the RNA expression of many other genes, with 15,595 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C5orf24-associated genes across cancer lineages are SMAD5, MBLAC2, and BDP1. Each is linked with C5orf24 in more than 6 cancer types. Because this analysis shows association rather than direction, both C5orf24-to-partner and partner-to-C5orf24 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C5orf24 versus SMAD5 in BRCA, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf24→partner) and Y-score (partner→C5orf24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SMAD5 →	+0.688	+0.396	<.001	<.001	3	7
BRCA	MBLAC2 →	+0.494	+0.209	<.001	<.001	3	7
BRCA	BDP1 →	+0.734	+0.378	.002	<.001	3	6
OV	IK →	+0.422	+0.280	.003	.009	3	6
HNSC	LARS1 →	+0.425	+0.282	.001	.001	3	6
OV	LEAP2 →	+0.583	+0.389	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,595 associations by consensus.

C5orf24 vs SMAD5 — BRCA

Explore this scatter interactively →