C5orf24

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C5orf24 mutation is significantly associated with the RNA expression of many other genes, with 2,074 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C5orf24-associated genes across cancer lineages are RNA5SP65, RNU6-492P, and RNU6-624P. Each is linked with C5orf24 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf24-to-partner and partner-to-C5orf24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP65 grouped by C5orf24-low versus C5orf24-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf24→partner) and Y-score (partner→C5orf24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRNA5SP65 →+0.504+4.520.001.00531
BLCARNU6-492P →+0.349+7.640<.001.00931
BLCARNU6-624P →+0.433+7.640<.001.00931
BLCARNU6-901P →+0.573+7.640<.001.00931
BLCAMIR518A2 →+0.396+7.640<.001.00931
UCECNUTF2P8 →+0.059+1.924.005.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,074 associations by consensus.

RNA5SP65 by C5orf24 expression — STAD

Box plot of RNA5SP65 in C5orf24-low vs C5orf24-high samples in STAD.

Explore this box plot interactively →

Exploration