C5orf17

Across TCGA pan-cancer cohorts, C5orf17 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated C5orf17 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher C5orf17 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C5orf17 expression acts as an unfavorable survival marker.

ESCA and KIRP are the cancer types where C5orf17 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.164	0.687	.002	21	view →
KIRP	DFS	Median	All	0.133	0.605	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

C5orf17–ESCA (OS)

Open the ESCA breakdown →