C5orf15

Across TCGA pan-cancer cohorts, C5orf15 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C5orf15 data layer compared with 23 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher C5orf15 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated C5orf15 expression acts as an unfavorable survival marker.

HNSC, COAD, and BLCA are the cancer types where C5orf15 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.122	0.680	.004	21	view →
COAD	DFS	Median	All	0.215	0.696	.013	15	view →
BLCA	OS	Median	All	0.188	0.687	.020	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

C5orf15–HNSC (DFS)

Open the HNSC breakdown →