Across TCGA patient cohorts, C5AR1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,982 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C5AR1-associated genes across cancer lineages are LILRB2, ITGAX, and PIK3R5. Each is linked with C5AR1 in more than 8 cancer types. Because this analysis shows association rather than direction, both C5AR1-to-partner and partner-to-C5AR1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5AR1→partner) and Y-score (partner→C5AR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LILRB2 →	+1.378	+0.945	<.001	<.001	3	9
COAD	ITGAX →	+1.544	+0.973	<.001	.002	3	9
GBM	PIK3R5 →	+1.217	+0.693	<.001	<.001	3	9
OV	CCR1 →	+1.308	+0.831	<.001	<.001	3	9
GBM	FPR1 →	+1.517	+0.708	<.001	<.001	3	9
OV	LILRB3 →	+1.087	+0.823	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,982 associations by consensus.

Exploration

C5AR1 survival (RNA) · tumor vs normal (RNA) · all C5AR1 data types