Across TCGA cell cohorts, C5AR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,427 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C5AR1-associated GO terms across cancer lineages are Complement component C5a signaling pathway, Sperm motility, and Flagellated sperm motility. Each is linked with C5AR1 in more than 14 cancer types. Because this analysis shows association rather than direction, both C5AR1-to-partner and partner-to-C5AR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C5AR1→partner) and Y-score (partner→C5AR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Complement component C5a signaling pathway →	+0.884	+1.657	.007	<.001	3	15
KIDNEY	Sperm motility →	-0.099	-1.093	<.001	<.001	3	11
KIDNEY	Flagellated sperm motility →	-0.099	-1.093	<.001	<.001	3	11
BONE	Cellular response to topologically incorrect protein →	+0.073	+0.694	.002	.003	3	11
BONE	Protein targeting to vacuole involved in autophagy →	+0.207	+0.516	<.001	<.001	3	11
KIDNEY	Regulation of intracellular mRNA localization →	+0.109	+1.187	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,427 associations by consensus.

Exploration

C5AR1 survival (RNA) · tumor vs normal (RNA) · all C5AR1 data types