C4orf51

Across TCGA pan-cancer cohorts, C4orf51 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated C4orf51 data layer compared with 19 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher C4orf51 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C4orf51 expression acts as an unfavorable survival marker.

LUAD and SKCM are the cancer types where C4orf51 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.111	0.835	<.001	36	view →
SKCM	OS	Median	All	0.257	0.781	.015	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

C4orf51–LUAD (OS)

Open the LUAD breakdown →