Across TCGA pan-cancer cohorts, C4orf47 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated C4orf47 data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher C4orf47 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated C4orf47 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

GBM and LSCC are the cancer types where C4orf47 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Median	All	0.930	0.647	.017	10	view →
LSCC	DFS	Median	II,III,IV	0.165	0.817	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: C4orf47 tumor-vs-normal RNA expression · all C4orf47 data types