Across TCGA patient cohorts, C4orf47 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C4orf47-associated genes across cancer lineages are FASN, JNK2, and PDK1_pS241. Each is linked with C4orf47 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf47-to-partner and partner-to-C4orf47 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf47→partner) and Y-score (partner→C4orf47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.540	+2.999	.004	.035	3	1
UCEC	JNK2 →	+0.192	+2.179	.045	.034	3	1
UCEC	PDK1_pS241 →	+0.184	+2.833	.026	.034	3	1
UCEC	Cyclin-B1 →	+0.602	+2.459	.026	.020	3	1
UCEC	PRDX1 →	+0.219	+2.459	.027	.020	2	1
UCEC	JNK_pT183_Y185 →	-0.207	-3.571	.010	.002	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

C4orf47 survival (RNA) · tumor vs normal (RNA) · all C4orf47 data types