Across TCGA patient cohorts, C4orf46 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,852 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C4orf46-associated proteins across cancer lineages are NCAPG, HPF1, and STMN1. Each is linked with C4orf46 in more than 7 cancer types. Because this analysis shows association rather than direction, both C4orf46-to-partner and partner-to-C4orf46 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf46→partner) and Y-score (partner→C4orf46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPG →	+0.507	+0.682	<.001	<.001	3	8
LSCC	HPF1 →	+0.428	+0.731	<.001	<.001	3	8
LSCC	STMN1 →	+0.678	+0.700	<.001	<.001	3	7
COAD	UBE2T →	+0.800	+0.775	<.001	.001	3	7
BRCA	NASP →	+0.559	+0.561	<.001	<.001	3	7
UCEC	NCAPG_S973 →	+0.824	+0.743	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,852 associations by consensus.

Exploration

C4orf46 survival (RNA) · tumor vs normal (RNA) · all C4orf46 data types