Across TCGA patient cohorts, C4orf46 protein abundance is significantly associated with the protein abundance of many other proteins, with 802 significant associations in total. OV shows the largest number of these associations.

The most reproducible C4orf46-associated proteins across cancer lineages are ABCC3_S911, AP5Z1, and ARSB. Each is linked with C4orf46 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf46-to-partner and partner-to-C4orf46 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf46→partner) and Y-score (partner→C4orf46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ABCC3_S911 →	-1.802	-0.662	.002	.001	3	2
LUAD	AP5Z1 →	+0.221	+0.559	.001	<.001	3	1
OV	ARSB →	+0.600	+0.621	<.001	<.001	3	1
OV	ASB9 →	+0.637	+0.924	<.001	<.001	3	1
OV	ATAD2 →	+0.948	+0.792	<.001	.002	3	1
OV	C2CD5_S817 →	-0.864	-0.834	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 802 associations by consensus.

Exploration

C4orf46 survival (RNA) · tumor vs normal (RNA) · all C4orf46 data types