Across TCGA cell cohorts, C4orf46 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,457 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C4orf46-associated GO terms across cancer lineages are Positive regulation of chromosome condensation, Nuclear division, and Positive regulation of cell cycle process. Each is linked with C4orf46 in more than 18 cancer types. Because this analysis shows association rather than direction, both C4orf46-to-partner and partner-to-C4orf46 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf46→partner) and Y-score (partner→C4orf46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of chromosome condensation →	+0.240	+1.203	<.001	<.001	3	18
OESOPHAGUS	Nuclear division →	+0.083	+0.839	.003	.003	2	19
PANCREAS	Positive regulation of cell cycle process →	+0.108	+1.016	<.001	<.001	3	18
OESOPHAGUS	Regulation of cell cycle checkpoint →	+0.113	+0.932	.002	<.001	3	17
BREAST	Regulation of sister chromatid segregation →	+0.120	+1.054	<.001	<.001	3	17
LUNG_SCLC	Error-prone translesion synthesis →	+0.109	+0.831	<.001	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,457 associations by consensus.

Exploration

C4orf46 survival (RNA) · tumor vs normal (RNA) · all C4orf46 data types