C4orf36

Across TCGA patient cohorts, C4orf36 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,165 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible C4orf36-associated GO terms across cancer lineages are Rescue of stalled ribosome, Error-free translesion synthesis, and Protein localization to Golgi apparatus. Each is linked with C4orf36 in more than 29 cancer types. Because this analysis shows association rather than direction, both C4orf36-to-partner and partner-to-C4orf36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rescue of stalled ribosome grouped by C4orf36-low versus C4orf36-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf36→partner) and Y-score (partner→C4orf36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Rescue of stalled ribosome →	+0.057	+0.695	<.001	<.001	3	30
THYM	Error-free translesion synthesis →	+0.077	+0.717	<.001	<.001	3	29
THYM	Protein localization to Golgi apparatus →	+0.068	+0.740	<.001	<.001	3	29
UVM	tRNA modification →	+0.036	+0.661	<.001	<.001	3	28
ESCA	Translational elongation →	+0.051	+0.328	.009	<.001	3	28
UVM	RNA modification →	+0.030	+0.543	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,165 associations by consensus.

Rescue of stalled ribosome by C4orf36 expression — UVM

Explore this box plot interactively →