C4orf36

Across TCGA patient cohorts, C4orf36 mutation is significantly associated with the RNA expression of many other genes, with 86 significant associations in total. COAD shows the largest number of these associations.

The most reproducible C4orf36-associated genes across cancer lineages are SLC20A1P3, PIGCP2, and RNU5F-2P. Each is linked with C4orf36 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf36-to-partner and partner-to-C4orf36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC20A1P3 grouped by C4orf36-low versus C4orf36-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf36→partner) and Y-score (partner→C4orf36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SLC20A1P3 →	+0.049	+7.640	<.001	.009	3	2
COAD	PIGCP2 →	+0.472	+5.693	<.001	.003	3	2
COAD	RNU5F-2P →	+1.657	+6.122	<.001	.002	3	2
BLCA	RNU6-1040P →	+0.343	+7.640	<.001	.009	3	2
BRCA	MIR4309 →	+0.332	+8.055	<.001	.007	3	1
UCEC	MIR4319 →	+0.382	+3.621	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

SLC20A1P3 by C4orf36 expression — BLCA

Explore this box plot interactively →