C4orf33

Across TCGA patient cohorts, C4orf33 protein abundance is significantly associated with the RNA expression of many other genes, with 6,418 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C4orf33-associated genes across cancer lineages are DSCC1, DDO, and ACTR3C. Each is linked with C4orf33 in more than 3 cancer types. Because this analysis shows association rather than direction, both C4orf33-to-partner and partner-to-C4orf33 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C4orf33 versus DSCC1 in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf33→partner) and Y-score (partner→C4orf33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DSCC1 →	-0.734	-0.568	<.001	.002	3	4
BRCA	DDO →	+0.693	+0.571	.001	.002	3	4
UCEC	ACTR3C →	+0.760	+0.759	.006	<.001	3	3
BRCA	TRIM5 →	+0.606	+0.756	.003	<.001	3	3
BRCA	ENPP4 →	+0.953	+0.715	<.001	<.001	3	3
GBM	RBM47 →	+0.666	+0.561	<.001	.003	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,418 associations by consensus.

C4orf33 vs DSCC1 — BRCA

Explore this scatter interactively →