C4orf33

Across TCGA patient cohorts, C4orf33 mutation is significantly associated with the RNA expression of many other genes, with 298 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C4orf33-associated genes across cancer lineages are DAZ4, PGBD4P2, and OR10D4P. Each is linked with C4orf33 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf33-to-partner and partner-to-C4orf33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAZ4 grouped by C4orf33-low versus C4orf33-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf33→partner) and Y-score (partner→C4orf33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DAZ4 →	+0.051	+4.254	<.001	.003	3	2
READ	PGBD4P2 →	+0.217	+6.257	<.001	.001	3	1
HNSC	OR10D4P →	+0.034	+4.912	<.001	.005	3	1
HNSC	RNU6-992P →	+0.371	+6.132	<.001	.001	3	1
HNSC	MIR30B →	+0.311	+4.655	<.001	.007	3	1
HNSC	MIR548H3 →	+0.340	+5.224	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 298 associations by consensus.

DAZ4 by C4orf33 expression — SKCM

Explore this box plot interactively →