C4orf33

Across TCGA patient cohorts, C4orf33 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C4orf33-associated genes across cancer lineages are Annexin-1, p62 Lck ligand, and PI3K-p85. Each is linked with C4orf33 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf33-to-partner and partner-to-C4orf33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by C4orf33-low versus C4orf33-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf33→partner) and Y-score (partner→C4orf33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.711	+2.827	.013	.035	3	1
UCEC	p62 Lck ligand →	+0.507	+2.817	.004	.036	2	1
UCEC	PI3K-p85 →	+0.315	+3.169	.006	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Annexin-1 by C4orf33 expression — UCEC

Explore this box plot interactively →