C4orf33

Across TCGA cell cohorts, C4orf33 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C4orf33-associated genes across cancer lineages are GHRHR, MAGEB4, and CPLX4. Each is linked with C4orf33 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf33-to-partner and partner-to-C4orf33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRHR grouped by C4orf33-low versus C4orf33-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf33→partner) and Y-score (partner→C4orf33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GHRHR →	+0.060	+4.054	.001	.004	3	1
LARGE_INTESTINE	MAGEB4 →	+0.019	+5.000	<.001	<.001	3	1
LARGE_INTESTINE	CPLX4 →	+0.024	+4.392	.004	.004	3	1
LARGE_INTESTINE	OR5M11 →	+0.132	+4.095	<.001	.003	3	1
LARGE_INTESTINE	FAM205A →	+0.023	+3.614	<.001	.006	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GHRHR by C4orf33 expression — LARGE_INTESTINE

Explore this box plot interactively →