C4orf3

Across TCGA patient cohorts, C4orf3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,119 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C4orf3-associated proteins across cancer lineages are LLGL1, PUS1, and RAI14. Each is linked with C4orf3 in more than 5 cancer types. Because this analysis shows association rather than direction, both C4orf3-to-partner and partner-to-C4orf3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C4orf3 versus LLGL1 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf3→partner) and Y-score (partner→C4orf3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LLGL1 →	+0.262	+0.425	<.001	<.001	3	6
OV	PUS1 →	-0.363	-0.620	<.001	.001	3	5
BRCA	RAI14 →	+0.380	+0.529	<.001	<.001	3	5
BRCA	GBE1 →	+0.430	+0.536	<.001	<.001	3	5
BRCA	SEC11C →	-0.828	-0.444	<.001	<.001	3	5
BRCA	ANXA2 →	+0.296	+0.361	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,119 associations by consensus.

C4orf3 vs LLGL1 — LSCC

Explore this scatter interactively →