C4orf3

Across TCGA cell cohorts, C4orf3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,445 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C4orf3-associated GO terms across cancer lineages are Endosomal transport, Positive regulation of cellular response to transforming growth factor beta stimulus, and Negative regulation of calcium ion export across plasma membrane. Each is linked with C4orf3 in more than 10 cancer types. Because this analysis shows association rather than direction, both C4orf3-to-partner and partner-to-C4orf3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by C4orf3-low versus C4orf3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf3→partner) and Y-score (partner→C4orf3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.046	+0.775	<.001	<.001	3	10
LARGE_INTESTINE	Positive regulation of cellular response to transforming growth factor beta stimulus →	+0.117	+0.981	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.098	+1.179	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of early endosome to late endosome transport →	+0.155	+1.293	<.001	<.001	3	9
LARGE_INTESTINE	Positive regulation of transforming growth factor beta receptor signaling pathway →	+0.117	+0.981	<.001	<.001	3	9
BONE	ERBB3 signaling pathway →	+0.172	+0.775	.001	.006	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,445 associations by consensus.

Endosomal transport by C4orf3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →