Across TCGA cell cohorts, C3orf70 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C3orf70-associated genes across cancer lineages are PTF1A, OR4N2, and GLT6D1. Each is linked with C3orf70 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf70-to-partner and partner-to-C3orf70 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf70→partner) and Y-score (partner→C3orf70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PTF1A →	+0.104	+4.977	<.001	.007	3	1
SKIN	OR4N2 →	+0.164	+4.977	<.001	.007	3	1
SKIN	GLT6D1 →	+0.012	+5.415	<.001	.004	3	1
SKIN	OR5V1 →	+0.012	+4.977	<.001	.007	3	1
SKIN	OR12D1 →	+0.006	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

C3orf70 survival (RNA) · tumor vs normal (RNA) · all C3orf70 data types