Across TCGA cell cohorts, C3orf70 mutation is significantly associated with the mutation status of many other genes, with 189 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible C3orf70-associated genes across cancer lineages are PRDM6, UPF2, and NLK. Each is linked with C3orf70 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf70-to-partner and partner-to-C3orf70 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf70→partner) and Y-score (partner→C3orf70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PRDM6 →	+5.824	+5.824	.002	.002	1	2
STOMACH	UPF2 →	+4.807	+4.807	.008	.008	1	2
STOMACH	NLK →	+4.807	+4.807	.008	.008	1	2
CNS	CHD4 →	+4.044	+5.000	.008	.008	1	2
CNS	SLF2 →	+5.044	+5.614	.003	.003	1	2
CNS	KDM3B →	+4.044	+5.000	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 189 associations by consensus.

Exploration

C3orf70 survival (RNA) · tumor vs normal (RNA) · all C3orf70 data types