Across TCGA patient cohorts, C3orf62 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C3orf62-associated genes across cancer lineages are Chk2, G6PD, and GSK-3a-b_pS21_S9. Each is linked with C3orf62 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf62-to-partner and partner-to-C3orf62 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf62→partner) and Y-score (partner→C3orf62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Chk2 →	-0.314	-3.321	.002	.009	3	2
UCEC	G6PD →	-0.349	-2.700	.016	.006	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.405	+1.884	.035	.030	3	1
UCEC	Heregulin →	-0.142	-2.584	.010	.010	3	1
UCEC	INPP4B →	-0.298	-2.459	.040	.019	3	1
UCEC	JNK_pT183_Y185 →	-0.159	-1.986	.035	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

C3orf62 survival (RNA) · tumor vs normal (RNA) · all C3orf62 data types