C3orf38

Across TCGA cell cohorts, C3orf38 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,287 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C3orf38-associated GO terms across cancer lineages are Transcription elongation by RNA polymerase II, Negative regulation of mitotic cell cycle phase transition, and Regulation of protein modification by small protein conjugation or removal. Each is linked with C3orf38 in more than 10 cancer types. Because this analysis shows association rather than direction, both C3orf38-to-partner and partner-to-C3orf38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription elongation by RNA polymerase II grouped by C3orf38-low versus C3orf38-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf38→partner) and Y-score (partner→C3orf38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Transcription elongation by RNA polymerase II →	+0.099	+0.604	<.001	<.001	3	11
OVARY	Negative regulation of mitotic cell cycle phase transition →	+0.053	+0.653	.002	<.001	3	10
OVARY	Regulation of protein modification by small protein conjugation or removal →	+0.075	+0.631	<.001	<.001	3	10
BREAST	Regulation of chromosome organization →	+0.097	+0.807	<.001	<.001	3	10
OVARY	Mitotic sister chromatid cohesion →	+0.129	+0.686	<.001	<.001	3	10
BREAST	Protein-DNA complex organization →	+0.055	+0.655	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,287 associations by consensus.

Transcription elongation by RNA polymerase II by C3orf38 expression — OVARY

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