C3orf33

Across TCGA pan-cancer cohorts, C3orf33 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C3orf33 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher C3orf33 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated C3orf33 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

PDAC, UCEC, and CCRCC are the cancer types where C3orf33 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.150	1.000	.049	12	view →
UCEC	DFS	Quartile	All	0.504	1.000	.031	8	view →
CCRCC	DFS	Median	All	1.000	0.434	.020	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

C3orf33–PDAC (OS)

Open the PDAC breakdown →