C3orf33

Across TCGA cell cohorts, C3orf33 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,605 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C3orf33-associated GO terms across cancer lineages are Tetrapyrrole metabolic process, Pigment biosynthetic process, and Phosphatidylinositol acyl-chain remodeling. Each is linked with C3orf33 in more than 11 cancer types. Because this analysis shows association rather than direction, both C3orf33-to-partner and partner-to-C3orf33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tetrapyrrole metabolic process grouped by C3orf33-low versus C3orf33-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf33→partner) and Y-score (partner→C3orf33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Tetrapyrrole metabolic process →	+0.091	+0.772	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Pigment biosynthetic process →	+0.093	+0.741	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Phosphatidylinositol acyl-chain remodeling →	+0.099	+0.686	.004	.001	3	11
LIVER	Porphyrin-containing compound metabolic process →	+0.104	+0.809	<.001	<.001	3	10
LIVER	Porphyrin-containing compound biosynthetic process →	+0.109	+0.603	.005	.009	3	10
LIVER	Heme biosynthetic process →	+0.105	+0.906	.007	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,605 associations by consensus.

Tetrapyrrole metabolic process by C3orf33 expression — LIVER

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