C3orf33

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C3orf33 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C3orf33-associated genes across cancer lineages are MAGEB4 and PGK2. Each is linked with C3orf33 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf33-to-partner and partner-to-C3orf33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by C3orf33-low versus C3orf33-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf33→partner) and Y-score (partner→C3orf33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEMAGEB4 →+0.012+5.415.009.00431
SKINPGK2 →+0.046+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MAGEB4 by C3orf33 expression — LARGE_INTESTINE

Box plot of MAGEB4 in C3orf33-low vs C3orf33-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration