C3orf20

Across TCGA patient cohorts, C3orf20 protein abundance is significantly associated with the RNA expression of many other genes, with 3,028 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C3orf20-associated genes across cancer lineages are CRISPLD2, SERPINE1, and RARRES2. Each is linked with C3orf20 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf20-to-partner and partner-to-C3orf20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C3orf20 versus CRISPLD2 in LSCC, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf20→partner) and Y-score (partner→C3orf20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CRISPLD2 →	-1.436	-0.511	<.001	<.001	3	2
LSCC	SERPINE1 →	-2.227	-0.652	<.001	.001	3	2
BRCA	RARRES2 →	-1.409	-0.400	.003	.009	3	2
BRCA	ACTA2 →	-1.460	-0.540	<.001	<.001	3	2
BRCA	PMP22 →	-1.673	-0.650	<.001	<.001	3	2
BRCA	VWA5A →	-1.367	-0.541	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,028 associations by consensus.

C3orf20 vs CRISPLD2 — LSCC

Explore this scatter interactively →