C3orf20

Across TCGA cell cohorts, C3orf20 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,133 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C3orf20-associated GO terms across cancer lineages are Regulation of TOR signaling, Cellular response to starvation, and Glycerophospholipid metabolic process. Each is linked with C3orf20 in more than 8 cancer types. Because this analysis shows association rather than direction, both C3orf20-to-partner and partner-to-C3orf20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of TOR signaling grouped by C3orf20-low versus C3orf20-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf20→partner) and Y-score (partner→C3orf20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of TOR signaling →	+0.033	+0.044	.004	.004	2	9
OVARY	Cellular response to starvation →	+0.050	+0.059	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid metabolic process →	+0.046	+0.137	<.001	.006	3	7
OVARY	Pre-miRNA processing →	+0.073	+0.052	.001	.004	3	7
PANCREAS	Positive regulation of post-translational protein modification →	+0.050	+0.059	<.001	.001	3	6
SKIN	RISC complex assembly →	+0.063	+0.038	.002	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,133 associations by consensus.

Regulation of TOR signaling by C3orf20 expression — LUNG_NSCLC_LUSC

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