C3orf20

Across TCGA cell cohorts, C3orf20 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C3orf20-associated genes across cancer lineages are C14orf177, LRRC55, and OC90. Each is linked with C3orf20 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf20-to-partner and partner-to-C3orf20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C14orf177 grouped by C3orf20-low versus C3orf20-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf20→partner) and Y-score (partner→C3orf20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C14orf177 →	+0.055	+4.922	<.001	.009	3	1
BLOOD_Leukemia	LRRC55 →	+0.006	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OC90 →	+0.006	+5.201	.003	.006	3	1
LARGE_INTESTINE	CPLX4 →	+0.046	+4.392	<.001	.004	3	1
LARGE_INTESTINE	MS4A14 →	+0.020	+4.054	<.001	.004	3	1
LARGE_INTESTINE	ARMH2 →	+0.221	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

C14orf177 by C3orf20 expression — BLOOD_Leukemia

Explore this box plot interactively →