C3orf18

Across TCGA pan-cancer cohorts, C3orf18 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C3orf18 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where higher C3orf18 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated C3orf18 expression acts as an unfavorable survival marker.

PRAD, UCEC, and COAD are the cancer types where C3orf18 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
COAD	OS	Median	All	0.168	0.805	.040	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

C3orf18–PRAD (DFS)

Open the PRAD breakdown →