C3orf14

Across TCGA patient cohorts, C3orf14 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,407 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C3orf14-associated proteins across cancer lineages are ISG20, ADGRE5, and RSL1D1. Each is linked with C3orf14 in more than 3 cancer types. Because this analysis shows association rather than direction, both C3orf14-to-partner and partner-to-C3orf14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C3orf14 versus ISG20 in LSCC, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf14→partner) and Y-score (partner→C3orf14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ISG20 →	-0.560	-0.530	<.001	.001	3	4
BRCA	ADGRE5 →	-0.388	-1.048	<.001	<.001	3	4
BRCA	RSL1D1 →	-0.450	-0.771	<.001	<.001	3	3
LSCC	SIPA1_S314 →	-0.443	-0.619	.005	.005	3	3
GBM	HP1BP3 →	-0.469	-0.675	.001	.002	3	3
BRCA	KRR1 →	-0.414	-0.949	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,407 associations by consensus.

C3orf14 vs ISG20 — LSCC

Explore this scatter interactively →