C3orf14

Across TCGA patient cohorts, C3orf14 protein abundance is significantly associated with the RNA expression of many other genes, with 1,237 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible C3orf14-associated genes across cancer lineages are CBY1, BRF2, and NHP2P1. Each is linked with C3orf14 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3orf14-to-partner and partner-to-C3orf14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C3orf14 versus CBY1 in BRCA, with a Pearson correlation of -0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf14→partner) and Y-score (partner→C3orf14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CBY1 →	-0.489	-0.563	.002	.001	3	1
BRCA	BRF2 →	+1.318	+0.591	.002	<.001	3	1
BRCA	NHP2P1 →	+2.995	+0.787	<.001	.001	3	1
BRCA	GADD45A →	-1.552	-0.789	.001	.001	3	1
BRCA	RNF170 →	+1.210	+0.687	.007	.006	3	1
BRCA	NQO2 →	+1.139	+0.591	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,237 associations by consensus.

C3orf14 vs CBY1 — BRCA

Explore this scatter interactively →