C3AR1

Across TCGA patient cohorts, C3AR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,900 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C3AR1-associated proteins across cancer lineages are RCSD1, SAMSN1_S23, and SKAP2. Each is linked with C3AR1 in more than 9 cancer types. Because this analysis shows association rather than direction, both C3AR1-to-partner and partner-to-C3AR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C3AR1 versus RCSD1 in GBM, with a Pearson correlation of 0.88.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C3AR1→partner) and Y-score (partner→C3AR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RCSD1 →	+0.707	+1.248	<.001	<.001	3	10
OV	SAMSN1_S23 →	+0.807	+1.193	<.001	<.001	3	10
GBM	SKAP2 →	+0.895	+1.184	<.001	<.001	3	10
HNSC	STK10 →	+0.434	+0.680	<.001	<.001	3	10
GBM	CD4 →	+0.856	+1.246	<.001	<.001	3	10
GBM	PTPRC →	+0.928	+1.276	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,900 associations by consensus.

C3AR1 vs RCSD1 — GBM

Explore this scatter interactively →