C3AR1

Across TCGA patient cohorts, C3AR1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,409 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C3AR1-associated genes across cancer lineages are EPB41L5, KLHL23, and SLC25A17. Each is linked with C3AR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both C3AR1-to-partner and partner-to-C3AR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C3AR1 versus EPB41L5 in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3AR1→partner) and Y-score (partner→C3AR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EPB41L5 →	-0.536	-0.477	<.001	<.001	3	3
GBM	KLHL23 →	-0.976	-0.607	<.001	<.001	3	3
OV	SLC25A17 →	-0.496	-0.739	.006	.003	3	3
OV	ATXN10 →	-0.493	-0.651	.002	.001	3	3
OV	SAAL1 →	-0.396	-0.522	.005	<.001	3	3
LSCC	HARS1 →	-0.371	-0.481	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,409 associations by consensus.

C3AR1 vs EPB41L5 — GBM

Explore this scatter interactively →