Across TCGA pan-cancer cohorts, C2orf91 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated C2orf91 data layer compared with 19 for mass-spec protein.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher C2orf91 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C2orf91 expression acts as an unfavorable survival marker.

DLBC are the cancer types where C2orf91 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Median	All	0.054	0.842	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: C2orf91 tumor-vs-normal RNA expression · all C2orf91 data types