C2orf81

Across TCGA cell cohorts, C2orf81 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,073 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C2orf81-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Cilium or flagellum-dependent cell motility, and Negative regulation of myoblast fusion. Each is linked with C2orf81 in more than 13 cancer types. Because this analysis shows association rather than direction, both C2orf81-to-partner and partner-to-C2orf81 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by C2orf81-low versus C2orf81-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf81→partner) and Y-score (partner→C2orf81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.134	+1.130	<.001	<.001	3	14
OVARY	Cilium or flagellum-dependent cell motility →	-0.074	-0.654	<.001	.004	2	14
STOMACH	Negative regulation of myoblast fusion →	+0.136	+1.130	<.001	<.001	3	13
KIDNEY	Sperm motility →	-0.089	-0.940	<.001	.004	3	13
OVARY	Cilium-dependent cell motility →	-0.074	-0.654	<.001	.004	2	14
KIDNEY	Cilium movement involved in cell motility →	-0.085	-1.134	.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,073 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by C2orf81 expression — STOMACH

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