C2orf80

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C2orf80 mutation is significantly associated with the RNA expression of many other genes, with 723 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2orf80-associated genes across cancer lineages are TUBBP11, OR7E97P, and RNU6-131P. Each is linked with C2orf80 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf80-to-partner and partner-to-C2orf80 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf80→partner) and Y-score (partner→C2orf80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMTUBBP11 →+0.185+4.394<.001<.00132
LUADOR7E97P →+0.036+4.912<.001.00332
LUADRNU6-131P →+0.196+4.444<.001.00632
LUADPPP1R11P1 →+0.226+3.813.003.00532
LUADTEX36-AS1 →+0.034+4.315<.001.00732
LUADLINC01974 →+0.107+3.700<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 723 associations by consensus.

Exploration