Across TCGA patient cohorts, C2orf80 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2orf80-associated genes across cancer lineages are A-Raf_pS299, IGFBP2, and INPP4B. Each is linked with C2orf80 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf80-to-partner and partner-to-C2orf80 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf80→partner) and Y-score (partner→C2orf80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.135	-3.169	.015	.019	3	1
UCEC	IGFBP2 →	-0.757	-3.000	.012	.036	3	1
UCEC	INPP4B →	-0.372	-3.321	.013	.010	3	1
UCEC	p70-S6K →	+0.216	+1.901	.016	.031	3	1
UCEC	Rab25 →	-0.475	-2.584	.002	.011	3	1
UCEC	Claudin-7 →	-0.674	-3.000	.004	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

C2orf80 survival (RNA) · tumor vs normal (RNA) · all C2orf80 data types