C2orf76

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C2orf76 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. COAD shows the largest number of these associations.

The most reproducible C2orf76-associated genes across cancer lineages are ABHD17AP9, RN7SKP178, and RNY3. Each is linked with C2orf76 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf76-to-partner and partner-to-C2orf76 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf76→partner) and Y-score (partner→C2orf76) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAABHD17AP9 →+0.074+7.640<.001.00932
COADRN7SKP178 →+0.576+5.893<.001.00231
COADRNY3 →+2.923+5.357<.001.00631
COADRNU6-108P →+0.488+6.122<.001.00231
COADRNU6-701P →+0.857+5.435<.001.00531
COADRNU6-49P →+0.381+6.721<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

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