C2orf73

Across TCGA cell cohorts, C2orf73 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,038 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible C2orf73-associated GO terms across cancer lineages are Protein localization to ciliary membrane, Positive regulation of intrinsic apoptotic signaling pathway, and Putrescine metabolic process. Each is linked with C2orf73 in more than 6 cancer types. Because this analysis shows association rather than direction, both C2orf73-to-partner and partner-to-C2orf73 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to ciliary membrane grouped by C2orf73-low versus C2orf73-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf73→partner) and Y-score (partner→C2orf73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Protein localization to ciliary membrane →	+0.064	+0.084	.001	<.001	3	7
STOMACH	Positive regulation of intrinsic apoptotic signaling pathway →	+0.078	+0.055	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Putrescine metabolic process →	+0.133	+0.050	.004	.006	3	5
KIDNEY	Regulation of syncytium formation by plasma membrane fusion →	+0.082	+0.171	.002	.001	2	6
CNS	Intraciliary anterograde transport →	+0.077	+0.070	<.001	.008	2	6
CNS	Cytoskeleton-dependent intracellular transport →	+0.025	+0.073	.002	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,038 associations by consensus.

Protein localization to ciliary membrane by C2orf73 expression — SKIN

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