Across TCGA patient cohorts, C2orf72 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C2orf72-associated genes across cancer lineages are SPINK6, ADH7, and MS4A5. Each is linked with C2orf72 in more than 1 cancer types. Because this analysis shows association rather than direction, both C2orf72-to-partner and partner-to-C2orf72 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C2orf72→partner) and Y-score (partner→C2orf72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	SPINK6 →	+0.160	+5.189	<.001	.006	3	1
SCLC	ADH7 →	+1.330	+4.847	<.001	.009	3	1
UCEC	MS4A5 →	+0.185	+4.690	.002	.003	3	1
UCEC	NF1P5 →	+0.188	+4.694	<.001	.007	3	1
UCEC	ANKRD60 →	+0.118	+4.852	<.001	.006	3	1
UCEC	MRPS22P1 →	+0.077	+4.937	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

C2orf72 survival (RNA) · tumor vs normal (RNA) · all C2orf72 data types